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Assignment #4.1: THE CONTENTS OF THE NUCLEUS

This is a graded assignment. The grade weight of this assignment is "2." A grade weight of 2 counts twice as much as a grade weight of 1, a grade weight of 4 counts twice as much as a grade weight of 2 and 4 times as much as a grade weight of 1, and so on.

 

THE CONTENTS OF THE NUCLEUS

The nucleus of any living active cell is bounded by a nuclear membrane. Inside the nucleus at certain times you can see, under high magnification, a number of ribbon-like molecules. These elongated molecules in the nucleus are called chromosomes.

Let us suppose that we are looking at the nucleus of an egg before it has been fertilized. Let us suppose, too, that this particular kind of egg has two chromosomes in its nucleus. Each chromosome is slightly different in size and chemical composition from the other. Our highest magnifications show us that a chromosome consists of an extremely slender thread coiled into so tight a spiral that it appears solid. A long coiled spring of fine wire might be used to represent a chromosome, if you were building a model of a nucleus. However, a wire is made of the same substance from end to end. Not so with a chromosome. Arranged along and amongst its coils there are proteins which help wind up the chromatin to prevent it getting tangled. If tiny beads were strung on your fine wire and then coiled into a tight spring, it might serve as a very imperfect model of a chromosome.

Each chromosome contains hundreds or even thousands of distinctly separable genes arranged in single file along its whole length. Each gene differs markedly (in chemical composition and function, for instance) from every other gene. Each gene has its own place in line on the chromosome, too.

Two chromosomes with their serially arranged genes are found within the nucleus of the egg cell we are examining. In the nucleus of a sperm of the same species there are also two chromosomes. When the sperm fertilizes the egg and the two nuclei fuse, the fused nucleus obviously contains four chromosomes. Before a fertilized egg starts to divide, the nucleus must pass through what is called the resting stage, or interphase. All four of the chromosomes uncoil within the nucleus in somewhat the way your coiled spring of fine wire might be pulled out of its spiral coil. The uncoiled chromosomes are so long and so slender and are so twisted about in crisscross fashion within the nucleus that you can see only a mass of tangled threads or perhaps only granules scattered about with no threads visible. When the nucleus is in this condition, the cell is usually said to be in interphase. However, the cell is not resting: it is alive and actively working. The interphase is merely the term applied to the stage when a cell is not dividing. A fertilized egg goes through a resting stage, then starts to divide. The division is called mitosis.


CELL DIVISION

Plants and animals grow by adding new cells to their bodies. Older cells divide to form new cells. This is one of the many ways God has enabled His creation to regenerate and live. In most plants, this dividing and adding of new cells continues as long as the plant is alive. In animals, the total number of cells does not usually increase after adulthood is reached, but cell division continues because new cells are needed to take the places of those that are destroyed or worn out.

The cell must go through a series of gradual changes before a single cell can become two cells. The process is known as mitosis, which is followed by cytokinesis. Together these are called cell division.

Prior to mitosis, significant changes take place within the nucleus. Each gene along the entire length of the chromosome duplicates itself; in other words, it builds another gene exactly like itself, with the result that there are now two identical chromosomes lying side by side, attached by the kinetochore. This chromosome duplication (DNA replication) takes place during the synthesis phase.

Click here to watch a video!

Learn about DNA in the cell's nucleus and how it is replicated and its role in cellular reproduction.

MULTIPLE CHOICE

Please choose the best answer for each of the following multiple choice questions below. (If necessary, open another window in Study Hall while you complete this assignment, so you are not timed out of the Academy system.) When you have completed your work, click on the “submit” button at the bottom of the page to turn in your assignment.

HOW MUCH HAVE YOU LEARNED?

Play the
CELL DIVISION GAME
with the chromosomes. Try both Mitosis and Meiosis. How many chromosomes or chromatids do you end up with at the end of each cell division?


McRel Biology
Benchmark 4th Ed.

Understands the processes of cell division and differentiation (e.g., meiosis, mitosis, embryo formation, cellular replication and differentiation into the many specialized cells, tissues, and organs that comprise the final organism; each cell retains the basic information needed to reproduce itself)

Reference Code

BD(SE,184;2E,109;CE,128;
IBE,33,41,64;AE,129;PE,52,56,*)

www.mcrel.org

Photo: Life Science, Prentice Hall

Mitosis has four phases. Prophase, Metaphase, Anaphase and Telophase. To see real cells in each of these phases,

Click Here.

Photo: Life Science, Prentice Hall